Microarray

Shipping Address

Shipping Address

2330, Inwood Road, Dallas, 75235, Texas
East Campus, BioCenter EB3.216
UT Southwestern Medical Center

Questions?

Please contact Indu Raman, Indu.Raman@UTSouthwestern.edu. [short code to display name, email for the lab manager for the core.]

16S V3-V4 Amplicon Sequencing

3’ Single cell RNA sequencing-10XGenomics MRL

5’ Single cell RNA sequencing-10XGenomics MRL

A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium

A short plus long-amplicon based sequencing approach improves genomic coverage and variant detection in the SARS-CoV-2 genome

A verified genomic reference sample for assessing performance of cancer panels detecting small variants of low allele frequency

Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases

Advancing NGS quality control to enable measurement of actionable mutations in circulating tumor DNA

Affymetrix

Amino acid signatures of HLA Class-I and II molecules are strongly associated with SLE susceptibility and autoantibody production in Eastern Asians

Applied Biosystems 7500 | Thermo Fisher Scientific

Association between Antibiotic Exposure and Systemic Immune Parameters in Cancer Patients Receiving Checkpoint Inhibitor Therapy

Association between body mass index, dosing strategy, and efficacy of immune checkpoint inhibitors

Autoantibodies to Perilipin-1 Define a Subset of Acquired Generalized Lipodystrophy

Autoantigen Microarray

Bacterial RNA Sequencing

Bioanalyzer

Bioanalyzer 2100 | Agilent Technologies

Blue Pippin DNA Size Selection System | Sage Science

Bo Zhang

Carlos Arana

Carlos Arana

Chaoying Liang

Chengsong Zhu

Chromium iX | 10x Genomics

Circadian clock cryptochrome proteins regulate autoimmunity

Comprehensive microRNA-seq transcriptomic profiling across 11 organs, 4 ages, and 2 sexes of Fischer 344 rats

CosMx Spacial Molecular Imager (SMI) | NanoString

Countess 3 Automated Cell Counter | Thermo Fisher Scientific

Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions

CXCR5 + PD-1 + follicular helper CD8 T cells control B cell tolerance

Cytassist | 10x Genomics

Cytosolic Nuclease TREX1 Regulates Oligosaccharyltransferase Activity Independent of Nuclease Activity to Suppress Immune Activation

Deep sequencing reveals a DAP1 regulatory haplotype that potentiates autoimmunity in systemic lupus erythematosus

Deep sequencing reveals a DAP1 regulatory haplotype that potentiates autoimmunity in systemic lupus erythematosus

Digital Spatial Profiling

DNA polymerase-α regulates the activation of type I interferons through cytosolic RNA:DNA synthesis

DNA/RNA Extraction

DNA/RNA Extraction MRL

Endocannabinoids Inhibit the Induction of Virulence in Enteric Pathogens

Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology

Fixed RNA Single cell RNA sequencing-10XGenomics MRL

Full-length 16S rRNA Gene Sequencing

GenePix 4400A Microarray Scanner | Molecular Devices

Genomics Core

GeoMx DSP Spatial Genomics | NanoString

Guangchun Chen

Hem-1 regulates protective humoral immunity and limits autoantibody production in a B cell-specific manner

HiSeq4K Sequencer 1 | Illumina

Hyperactivated PI3Kδ promotes self and commensal reactivity at the expense of optimal humoral immunity

IL10 restrains autoreactive B cells in transgenic mice expressing inactive RAG1

Illumina iScan System

Impact of Bead-Beating Intensity on the Genus- and Species-Level Characterization of the Gut Microbiome Using Amplicon and Complete 16S rRNA Gene Sequencing

In-Depth Evaluation of a Case of Presumed Myocarditis After the Second Dose of COVID-19 mRNA Vaccine

Indu Raman

Integration of Genome-Wide DNA Methylation and Transcription Uncovered Aberrant Methylation-Regulated Genes and Pathways in the Peripheral Blood Mononuclear Cells of Systemic Sclerosis

IRF1 governs the differential interferon-stimulated gene responses in human monocytes and macrophages by regulating chromatin accessibility

IRGM1 links mitochondrial quality control to autoimmunity

iScan System | Illumina

ITS (Internal transcribed spacer) Sequencing for Fungi Detection

Jinchun Zhou

Loss-of-function variants in SAT1 cause X-linked childhood-onset systemic lupus erythematosus

Lower baseline autoantibody levels are associated with immune-related adverse events from immune checkpoint inhibition

Luminex

LUNA-FL Dual Fluorescence Cell Counter | Logos Biosystems

Mei Yan

Meso Scale Discovery

Meso Scale Discovery (MSD) Assay Service | NorthEast BioLab

Metatranscriptomics Illumina MRL

Microarray Core

Microbiome Core

MinION Mk1C | Nanopore

MiSeqDx | Illumina

Molecular Signature Predictive of Long-Term Liver Fibrosis Progression to Inform Antifibrotic Drug Development

Molecular signatures of long-term hepatocellular carcinoma risk in nonalcoholic fatty liver disease

mRNAseq-Strand Specific Library Preparation

N-Counter Sprint Profiler

Nanodrop 2000 | Thermo Fisher Scientific

Nanopore Training: Essentials to advanced

Native RNA Sequencing on Nanopore

NextSeq550 | Illumina

NovaSeq 6000 System | Illumina

Pathogen-Genome Sequencing Nanopore MRL

Pathogen-Genome Sequencing on Illumina

Peripheral Blood Mononuclear Cell Gene Expression in Chronic Obstructive Pulmonary Disease: miRNA and mRNA Regulation

Picogreen Victor X3 | Perkin Elmer

Pratibha Selvakumar

Prevalence and pathogenicity of autoantibodies in patients with idiopathic CD4 lymphopenia

Quanterix Simoa HD-X Analyzer

Qubit Flex | Thermo Fisher Scientific

RAD51 interconnects between DNA replication, DNA repair and immunity

Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity

Regulatory T Cell-Derived TGF-β1 Controls Multiple Checkpoints Governing Allergy and Autoimmunity

Resistin-like Molecule α Provides Vitamin-A-Dependent Antimicrobial Protection in the Skin

Sample News Post

March 15, 2022/by Academic Web Pages

Sample Quality Control

Sample Quality Control-MRL

Serum amyloid A delivers retinol to intestinal myeloid cells to promote adaptive immunity

Shotgun-Metagenomics Illumina MRL

Single cell Multiomics-10XGenomics MRL

Single cell surface protein profiling-10XGenomics MRL

Small proline-rich protein 2A is a gut bactericidal protein deployed during helminth infection

Sputum Antineutrophil Cytoplasmic Antibodies in Serum Antineutrophil Cytoplasmic Antibody-Negative Eosinophilic Granulomatosis with Polyangiitis

Srisha Sridharan

Tao Chen

Tapestation 4150 | Agilent Technologies

Tet2 and Tet3 in B cells are required to repress CD86 and prevent autoimmunity

The impact of Staphylococcus aureus genomic variation on clinical phenotype of children with acute hematogenous osteomyelitis

The microbiota coordinates diurnal rhythms in innate immunity with the circadian clock

Transancestral mapping and genetic load in systemic lupus erythematosus

Tulasi Relangi

Ultra-Sensitive Biomarker Detection | Quanterix

Xenium | 10x Genomics

Microarray Team

Indu Raman
Microarray Core Lab Manager
Expertise: Luminex, Nanostring GeoMx-DSP
Indu.Raman@UTSouthwestern.edu
214-645-6071
Guangchun Chen
Microarray Core Research Scientist
Expertise: micRNA , qPCR, DSP
Guangchun.Chen@UTSouthwestern.edu
214-645-6072
Tao Chen
Microarray Core Research Associate
Expertise: Protein array, SNP genotyping
Tao.Chen@UTSouthwestern.edu
214-645-6071
Mei Yan
Microarray Core Research Scientist
Expertise: Protein array, MSD
Mei.Yan@UTSouthwestern.edu
214-645-6071
Chengsong Zhu
Microarray Core Biostatistical Consultant-II
Expertise: Data analysis, bioinformatics
Chengsong.Zhu@UTSouthwestern.edu
214-645-6071
Pratibha Selvakumar
Microarray Core Research Associate
Expertise: SIMOA, Luminex
Pratibha.Selvakumar@UTSouthwestern.edu
214-645-6071

Selected Publications

[need short code to display by core]